http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270889/
Fat Reduction by Topical Waist Applications May Actually Work
George D. Lundberg, The Medscape Journal of Medicine; Harvard School of Public Health, Boston, Massachusetts; Stanford University School of Medicine, Stanford, California Author's email: glundberg@medscape.net ;
Disclosure: George D. Lundberg, MD, has disclosed that he is a full-time employee of WebMD Health. Dr. Lundberg has also disclosed that he owns stock options in WebMD and HLTH Corporation.
This is the Medscape Medical Minute. I'm Dr. George Lundberg. So many people struggle with body fat, generalized and localized. How wonderful it would be if a person could rub on a topical cream and make the fat go away. Three researchers at Louisiana State University recently published in the journal Diabetes, Obesity & Metabolism, a randomized, placebo-controlled clinical trial that asked this question. If 50 adult men and women with body mass indices over 27 kg/m were on a prescribed 1200-calorie balanced diet and a walking program, would the addition of the application of 0.5% aminophylline cream to the waist twice a day change BMI and waist circumference? After 12 weeks, the answer was yes, 11 cm less in the cream group and 5 cm less in the control group – a significant difference. BMI decreased in both groups; waist-to-hip ratios declined; women lost more; aminophylline blood levels were undetectable.[1] Small sample size, but an exciting result, worthy of further study.
I'm Dr. George Lundberg, reporting.
1. Caruso MK, Pekarovic S, Raum WJ, Greenway F. Topical fat reduction from the waist. Diabetes Obes Metab. 2007;9:300–303. [PubMed]
If you do decide to try this out please let me know. When I experimented with aminophylline cream a few years ago on a few clients didnt notice anything dramatic. Trust me, if this 'worked" everyone would know about it.
ReplyDeleteAminophylline
ReplyDeletehttp://en.wikipedia.org/wiki/Aminophylline
Like other methylated xanthine derivatives, aminophylline is both a
1.competitive nonselective phosphodiesterase inhibitor [2] which raises intracellular cAMP, activates PKA, inhibits TNF-alpha [3][4...] and leukotriene [5] synthesis, and reduces inflammation and innate immunity [5] and
2.nonselective adenosine receptor antagonist [6].
Your fat cells first line of defence against fat loss is INSULIN! So the first goal of anyone trying to lose fat, especially trouble spots like abs, thighs, and butt, should be to lower insulin levels ( low-carb / ketogenic / low glycemic l...oad diets will help you here), not finding a rub on cream that will supposedly "We conclude that topical fat reduction for women's thighs can be achieved without diet or exercise." Greenway FL, Bray GA, Heber D.
ReplyDeleteThis isnt to say this cream formula isnt helpful (it can be if your insulin levels are low). In the future I will expand on the spot-reducing topic further.